Anthrax (Deadly Diseases and Epidemics) by Janet M. Decker

By Janet M. Decker

Specialists within the box of microbiology inform the nice detective tales of ways a few of the world's best-known lethal disease-causing microbes have been first remoted, pointed out, and studied. Readers learn the way those lethal viruses and micro organism reason affliction and what steps were taken to get rid of them. most typically linked to animals equivalent to farm animals, the infectious affliction anthrax lately entered the highlight for its power use as a weapon of organic battle opposed to people.

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Extra info for Anthrax (Deadly Diseases and Epidemics)

Example text

Within three hours, the spores germinated inside macrophage vesicles. Bacillus anthracis producing lethal toxin and edema toxin remained alive inside the macrophages and began to disrupt their vesicle membranes. In contrast, mutant Bacillus anthracis that could not make PA, lethal factor, or edema factor were killed during the three-hour experiment and the macrophages remained h e a l t h y. These findings suggest that toxin production protects Bacillus anthracis from macrophage killing. Once the macrophages die and release Bacillus anthracis, the bacterium divides and produces more toxin to kill other cells from the outside.

The man vi s i ted his doctor and began anti bi o tic therapy. The next day he was ad m i t ted to the hospital with fever, ch i ll s , and pain and swelling in his arm . He was d i a gnosed with cut a n eous anthrax and given intravenous anti bi o tics. He recovered and retu rned to work in late August. No anthrax bacteria could be isolated f rom his bl ood or wound ti s su e , but his bl ood did con t a i n antibodies to anthrax. The man had not traveled out of s t a te or been expo s ed to wild or domestic animals.

As bl ood flows from an animal dying of anthrax, the bacteria in the blood quickly form spores to protect themselves from the harsh environment in the soil. Spores are anthrax bacteria in a state of suspended animation, protected by a thick coat from drying out. Animals that die from anthrax leave spores in the soil. Decades later, anthrax can still infect other animals that ingest or inhale the spores as they graze. 4 Anthrax outbreaks have decreased significantly in the United States over the last 50 years.

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